Details

Alfuzosin is used for treating symptoms of benign prostatic hyperplasia (BPH) in men with an enlarged prostate. It may also be used for other conditions as determined by your doctor. Alfuzosin is an alpha-blocker. It works by blocking receptors in the lower urinary tract, causing smooth muscles in the bladder neck and prostate to relax. This relaxation improves urine flow and reduces the symptoms of BPH. Do not use Alfuzosin is you are allergic to any ingredient in Alfuzosin, you have moderate to severe liver problems or you are taking an alpha-blocker.

Typical Uses

Alfuzosin is used by men to treat the symptoms of an enlarged prostate (benign prostatic hyperplasia-BPH). It does not shrink the prostate, but it works by relaxing the muscles in the prostate and the bladder. This helps to relieve symptoms of BPH such as difficulty in beginning the flow of urine, weak stream, and the need to urinate often or urgently (including during the middle of the night). Alfuzosin may also be used to help your body "pass," or get rid of, kidney stones through urination.

Side Effects

Alfuzosin use may lead to drowsiness, weakness, depression, headache, dizziness and lack of energy, low blood pressure, fainting, fast heartbeat, palpitation, chest pain and flushing, dry mouth and gastrointestinal disturbances, swelling, blurred vision, runny nose, erectile disorders and hypersensitivity reactions.

Drug Interactions

• Alfuzosin+amiodarone- Using amiodarone together with alfuzosin can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect.

• Alfuzosin+anagrelide- Using anagrelide together with alfuzosin can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect.

• Alfuzosin+bepridil- Using bepridil together with alfuzosin can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect.

• Alfuzosin+ceritinib- Using ceritinib together with alfuzosin can increase the risk of an irregular heart rhythm that may be serious and potentially life-threatening, although it is a relatively rare side effect.

• Alfuzosin+darunavir- Using alfuzosin together with darunavir is not recommended. Combining these medications may significantly increase the blood levels and effects of alfuzosin. This can cause blood pressure to fall excessively and heart rate to increase, especially when you rise from a sitting or lying position.

• Alfuzosin+erythromycin- Using alfuzosin together with erythromycin is not recommended. Combining these medications may significantly increase the blood levels and effects of alfuzosin. This can cause blood pressure to fall excessively and heart rate to increase, especially when you rise from a sitting or lying position.

Mechanism of action

Alfuzosin belongs to group of medicines called alpha-blockers. It works by blocking the action of chemical adrenalin, thereby relaxing the muscles in the bladder and prostate, relieving difficulty in urination.

Pregnancy Category : B