Details

Adapalene is a topical (applied to the skin) medication similar to vitamin A. It helps the skin renew itself. Adapalene topical is used to treat severe acne in people who are at least 12 years old. It belongs to a class of medications called retinoids. It works by affecting the growth of cells and decreasing swelling and inflammation.

Typical Uses

Adapalene is used to treat acne. Adapalene is in a class of medications called retinoid-like compounds. It works by stopping pimples from forming under the surface of the skin. Adapalene comes as a gel, a solution (liquid), and a cream to apply to the skin. The solution comes in a glass bottle with an applicator and as individual pledgets (medicated wipes for one time use). It is usually applied once a day at bedtime.

Adapalene controls acne but does not cure it. Your acne may get worse during the first few weeks of treatment, and it may take 8 to 12 weeks or longer before you feel the full benefit of adapalene. Pimples can take 6 to 8 weeks to form under the skin, and during the first weeks of your treatment, adapalene may bring these pimples to the skin surface. Continue to use adapalene even if your acne worsens or you do not see much improvement at first. Do not stop using adapalene without talking to your doctor.

Side Effects

Adapalene may cause a brief sensation of warmth or stinging after application. Skin redness, dryness, itching, scaling, mild burning, or worsening of acne may occur during the first 2-4 weeks of using adapalene. Tell your doctor immediately if any of these unlikely but serious side effects occur: very red/irritated skin, an intense burning sensation, eye redness and watering, eyelid swelling, skin discolouration. Serious allergic reactions to adapalene are highly unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction may include rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

Drug Interactions

• Adapalene+isotretinoin- Using isotretinoin together with adapalene topical may increase skin irritation. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs.

Mechanism of action

Adapalene belongs to class of medications called retinoid-like compounds. It exhibits an anti-inflammatory effect and reduces soreness and irritation. It works by stopping pimple formation under the surface of the skin.

Pregnancy Category : C