Details of Acyclovir Salt (Generic Drug)

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Details

Acyclovir is an antiviral drug which is used to treat infections caused by certain types of viruses. It treats cold sores around the mouth (caused by herpes simplex), shingles (caused by herpes zoster) and chickenpox. Acyclovir is also used to treat outbreaks of genital herpes. In people with frequent outbreaks, acyclovir is used to help reduce the number of future episodes. However, it is not a cure for these infections. The viruses that cause these infections continue to live in the body even between outbreaks. Acyclovir decreases the severity and length of these outbreaks. It helps the sores heal faster, keeps new sores from forming, and decreases pain. Acyclovir may also help reduce how long pain remains after the sores heal. In addition, in people with a weakened immune system, acyclovir can decrease the risk of the virus spreading to other parts of the body and causing serious infections.


Typical Uses

Acyclovir is prescribed for herpes simplex, genital herpes, herpes zoster and chickenpox. It slows down the growth and spread of the herpes virus. Acyclovir is also sometimes used to treat eczema herpeticum, herpes infections of the skin, eyes, nose, and mouth in patients with human immunodeficiency virus (HIV), and to treat oral hairy leukoplakia a condition that causes hairy white or gray-coloured patches on the tongue or inside of the cheek.


Side Effects

Taking Acyclovir may cause severe allergic reactions, fever, headache, pain, difficulty sleeping, angioedema and swelling in your hands, aggressive behaviour, agitation, unsteadiness, coma, confusion, decreased consciousness, confusion, dizziness, hallucinations, numbness, burning, or tingling in the arms or legs, epilepsy, drowsiness and tremors, diarrhoea, gastrointestinal distress, vomiting and nausea, decrease in white blood cells and platelets, temporary inability to move parts of your body, Kidney failure, elevated blood urea nitrogen levels, blood in urine and urinating less than usual or not at all.


Drug Interactions

• Acyclovir+cidofovir- Using cidofovir together with acyclovir is not recommended. Cidofovir may cause kidney damage, and combining it with other medications that can also affect the kidney such as acyclovir may increase that risk.

• Acyclovir+sirolimus- Sirolimus may cause kidney problems, and combining it with other medications that can also affect the kidney such as acyclovir may increase that risk. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications.

• Acyclovir+tacrolimus- Tacrolimus may cause kidney problems, and combining it with other medications that can also affect the kidney such as acyclovir may increase that risk. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications.

• Acyclovir+tizanidine- Using tizanidine together with acyclovir is generally not recommended. Combining these medications may significantly increase the blood levels and effects of tizanidine. This may cause blood pressure to fall excessively, especially when you rise from a sitting or lying position.


Mechanism of action

Acyclovir is an antiviral drug and belongs to class called synthetic nucleoside analogues. It works by blocking the process by which the virus grows and multiplies. Acyclovir thus stops the virus from spreading in the body.


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