Details of Acenocoumarol Salt (Generic Drug)



Acenocoumarol is an anticoagulant that functions as a vitamin K antagonist (like warfarin). It is a derivative of coumarin and is marketed under the brand names Sintrom and Sinthrome. Anticoagulants decrease the clotting ability of the blood and therefore help to prevent harmful clots from forming in the blood vessels. These medicines are sometimes called blood thinners, although they do not actually thin the blood. They also will not dissolve clots that already have formed, but they may prevent the clots from becoming larger and causing more serious problems. They are often used as treatment for certain blood vessel, heart, and lung conditions. In order for an anticoagulant to help without causing serious bleeding, it must be used properly and all of the precautions concerning its use must be followed exactly.

Typical Uses

Acenocoumarol is used to prevent and treat blood clots in blood vessels e.g. Atrial fibrillation (disorder in rhythm and speed of heart where there is an increased the chances of clots formation in the body, causing strokes), after heart attack, artificial heart valves, deep venous thrombosis (blood clot in the leg) and pulmonary embolism (blood clot in the lung).

Side Effects

Acenocoumarol may cause backache, vomiting, hair loss, blood in the urine or stools, itching of skin, heavy bleeding from cuts or wounds internal bleeding, raised, Common side effects of Acenocoumarol are unusual bleeding such as bleeding from the gums, inflammation of skin, the signs of which include-stomach or abdominal pain, nose bleeding, unexplained bruising, fever, loss of appetite, joint pain or stiffness, urge to vomit, heavy menstrual periods, coughing or vomiting blood, blurred vision. Acenocoumarol can also lead to severe allergic reactions including pale red, dizziness, severe headache, itchy skin rash however, these are rare.

Drug Interactions

• Acenocoumarol+Acetaminophen

• Acenocoumarol+Allopurinol

• Acenocoumarol+Amiodarone

• Acenocoumarol+Chloramphenicol

• Acenocoumarol+Primaquine

Mechanism of action

Acenocoumarol is prescribed to prevent unwanted clots from forming if you have a condition that puts you at risk of this happening, such as atrial fibrillation, or if you have had a heart valve replacement. It is also given to prevent any clots that may have already formed in the blood vessels of your legs, lungs or heart from becoming larger and causing problems. Another anticoagulant, called warfarin, is usually prescribed in preference to acenocoumarol. However, if warfarin is not suitable for you, you may be prescribed acenocoumarol instead.

Pregnancy Category : X

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