Test Details & Preparation

• Apolipoprotein A-I test is done to determine whether or not you have an adequate level of Apo A-I, especially if you have a low level of high-density lipoprotein (HDL-C), and to help determine your risk of developing cardiovascular disease (CVD).


• Apolipoprotein A-I test is performed when you have high cholesterol and triglycerides (hyperlipidemia) and/or a family history of CVD when your health care provider is trying to assess your risk of developing heart disease when monitoring the effectiveness of lipid treatment or lifestyle changes.


• A blood sample drawn from a vein in your arm blood from the prick of a baby's heel or finger for Apolipoprotein A-I test.


• No test preparation is required for Apolipoprotein A-I test however this test is often ordered at the same time as other tests that require fasting, so you may be instructed to fast for 12 hours prior to having this test.


• Low levels of Apo A-I are associated with low levels of HDL and impaired clearance of excess cholesterol from the body. Low levels of apo A-I, along with high concentrations of Apo-B, are associated with an increased risk of cardiovascular disease.


• Apo A-I may decrease with chronic kidney disease, use of drugs such as: androgens, beta blockers, diuretics, and progestin, smoking, uncontrolled diabetes, obesity and more.


• Apo A-I may increase with use of drugs such as: carbamazepine, estrogens, ethanol, lovastatin, niacin, oral contraceptives, phenobarbital, pravastatin, and simvastatin, physical exercise, pregnancy, weight reduction and use of statins.