• Test Code - PL0109
  • Test Name - Androstenedione (A4)
  • Views - 282 Views
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Test Details & Preparation

Androstenedione test is an automated blood test which is performed to measure the amount of androstenedione present in your blood. It is done to confirm various cases of amenorrhea, hirsutism, infertility and polycystic ovarian syndrome.

Androstenedione is secreted mainly by the adrenal gland and production is partially controlled by ACTH hormone. Androstenedione is a main sex- steroid antecedent.

  • Androstenedione is used to evaluate the function of the adrenal gland and the ovaries or the testicles as well as the production of hormones related to the development of male sex organs and physical characteristics (androgens).
  • Androstenedione is the most common way to determine the cause of symptoms of excess androgens in a woman who has an elevated testosterone level.
  • Androstenedione level evaluates and adrenal gland function and helps differentiate androgen-secreting conditions that are caused by the adrenal glands from those that originate in the ovaries or testicles.
  • Androstenedione level helps determine the cause of delayed puberty and investigate suspected ovarian or testicular failure.
  • Androstenedione level helps diagnose the cause of male physical characteristics (virilisation) in young girls and early (precocious) puberty in young boys.
  • Androstenedione, along with other hormone tests may be ordered whenever excess androgen production is suspected or when a doctor wants to evaluate a person's adrenal gland, ovarian, or testicular function.
  • Androstenedione may be ordered when a female infant has external sex organs that are not clearly male or female or when a young girl develops male physical features.
  • A blood sample is obtained by inserting a needle into a vein in the arm for Androstenedione.
  • In menstruating women, the sample should be collected one week before or after a menstrual period.
  • An elevated level of Androstenedione indicates increased adrenal, ovarian or testicular production. It may also indicate an adrenal tumour, adrenal cancer, adrenal hyperplasia, or congenital adrenal hyperplasia (CAH).
  • A low level of Androstenedione may be due to adrenal gland dysfunction, adrenal insufficiency, or to ovarian or testicular failure.


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