• Test Code - PL0020
  • Test Name - A.C.T.H
  • Views - 867 Views
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Test Details & Preparation


  • ACTH test is done to help diagnose adrenal and pituitary diseases such as Cushing syndrome, Cushing disease, Addison disease, adrenal tumours and pituitary tumours.

  • ACTH test is performed when you have symptoms associated with excess or deficient cortisol production when your doctor suspects that you have a hormone imbalance that could be caused by a problem with your pituitary or adrenal glands.

  • A blood sample drawn from a vein in your arm for an ACTH test.

  • Your doctor may request that you fast overnight before testing. Blood is typically drawn in the morning, about 8 A.M.

  • In many cases, the interpretation of the results can be complex. Levels of both ACTH and cortisol vary throughout the day. Normally, ACTH will be at its highest level in the morning and lowest at night. It will stimulate cortisol production, which will follow the same daily pattern but will rise after ACTH does and fall to its lowest level very late in the evening.

  • An increased ACTH result can mean that a person has Cushing disease, Addison disease, or ectopic ACTH-producing tumours. A decreased ACTH result can be due to an adrenal tumour, steroid medication, or hypopituitarism.

  • It is impossible to reliably distinguish Cushing disease and ectopic ACTH from cortisol and ACTH measurement alone. A variety of other tests may be required.


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