Test Details & Preparation
5'-nucleotidase (5'-NT) is a protein produced by the liver. A test can be done to measure the amount of this protein in your blood.
Blood is drawn from a vein. Most of the time, a vein on the inside of the elbow or the back of the hand is used. The site is cleaned with germ-killing medicine (antiseptic). The doctor wraps an elastic band around the upper arm to apply pressure to the area and make the vein swell with blood.
Next, the provider gently inserts a needle into the vein. The blood collects into an airtight vial or tube attached to the needle. The elastic band is removed from your arm. Once the blood has been collected, the needle is removed, and the puncture site is covered to stop any bleeding.
Your doctor may tell you to stop taking some medicines that could interfere with the test. Drugs that may affect results include acetaminophen (Tylenol), halothane, isoniazid, methyldopa and nitrofurantoin.
Your doctor may order this test if you have signs of a liver problem. It is used mostly to tell if the high protein level is due to liver damage or skeletal muscle damage.
The normal value is 2 to 17 units per litre. Normal value ranges may vary slightly among different laboratories. Talk to your doctor about the meaning of your specific test results.
Greater than normal levels may indicate cholestasis (when bile, which is made by the liver to help digest fats, is blocked from flowing out of the liver destruction of liver cells liver inflammation loss of blood and oxygen to the liver liver tumour or use of a liver-damaging drug.